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Previous studies have demonstrated that traditional markers of fluid balance correlate poorly with acid base status and respiratory function.
Many studies have focused on the prediction of fluid responsiveness, and many different dynamic markers of fluid responsiveness have been studied in recent years [ 1, 5– 7].
Markers of fluid responsiveness were compared between responders (CI ≥15%) and nonresponders to a colloid fluid challenge (5 ml/kg IBW).
These dynamic markers of fluid responsiveness are more reliable than traditional techniques [ 72] and more practical to use than fluid challenges guided by stroke volume change.
The present study evaluated the effect of pioglitazone or insulin glargine on cardiac function and size as well as on surrogate markers of fluid retention such as weight, haemoglobin and natriuretic peptides.
Notably, despite the amount of clinical data supporting the uselessness of static parameters (CVP, PAOP) as markers of fluid responsiveness [ 27, 28], a significant proportion of intensivists still use these static indices.
Similar(52)
Objective: To verify the reliability of different markers of fluid-responsiveness during off-pump cardiac surgery (OPCAB).
Rather than abandoning a time-honored therapeutic strategy, perhaps we should first strive to find better clinical markers of fluid-responsiveness. Clearly, the traditional markers used to date (heart rate, urine output, blood pressure, capillary refill, central venous pressure, pulmonary artery occlusion pressure, etc).
The body weight, though subject to difficulties and possible errors in measurement is an indirect marker of fluid overload.
In our patients, mean ΔSVC, which has previously been validated as a marker of fluid responsiveness [31], was similar in survivors and in non-survivors.
Besides routine ICU measurements, including risk factors for developing AKI, three study measurements were performed at inclusion: RRI, sublingual sidestream dark field imaging (SDF) to visualise microcirculation, and Bioelectrical Impedance Analysis (BIA) as a marker of fluid status.
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