His research focuses on using biologic markers of exposure, early biologic effect, and genetic susceptibility in epidemiologic studies of occupational and environmental causes of cancer.
If the molecular markers of exposure are transient and the desired parameter is lifetime exposure, a review of medical records or self-report may be more valid.
Nitro-derivatives of PAH can act as markers of exposure to diesel exhaust, gasoline exhaust, or general combustion sources.
It is therefore of first importance to determine the sensitivity of immune endpoints as good markers of exposure to PAHs in bivalves.
Our findings demonstrate both quantitative and qualitative differences in T cell reactivity to HIV between HESN (HIV exposed seronegative) and HUSN (HIV unexposed seronegative) subject groups but do not discriminate as to whether they represent markers of exposure or of protection against HIV infection.
These proteins, if immunogenic, may represent ideal candidates for the development of serological markers of exposure to anopheline mosquitoes.
In particular, markers of exposure to different types of respiratory pathogens may yield diverse sets of markers that can be used to differentiate exposure.
The strengths of present study include its high participation rate (>95%), and both genotyping and internal biological markers of exposure available.
Among these proteins, the so-called Salivary Gland proteins (SG1-8) have been reported to be Anopheles spp.-specific and may represent potential candidate for elaborating genus-specific markers of exposure [19].
For all these reasons, the next stage consisted of validating only gSG6-P1 and gSG6-P2 peptides as markers of exposure in a larger immuno-epidemiological analysis according to entomological data.
The main results regarding air pollution and CIMT progression are presented in Table 3, Figure 1 and Figure 2. In general, both proximity markers of exposure and P2.5 were positively associated with CIMT progression.
