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Common protein markers of epithelial and mesenchymal phenotypes are listed.
Several genes from exC3, including the S100 and SPRR genes, CST6 and SERPINB3 are used as indirect markers of epithelial differentiation in malignancy, where loss of differentiation is associated with poor outcomes.
Cytokeratins (CKs) are critical markers of epithelial differentiation [ 19].
Cytokeratins are specific markers of epithelial cancer cells in bone marrow.
Therefore identification of noninvasive and accessible markers of epithelial ovarian carcinoma (EOC) is valuable.
7, 24 Two of the widely studied markers of epithelial and mesenchymal phenotypes are E-cadherin and β-catenin, respectively.
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Positive markers of epithelial-mesenchymal transition (EMT) in head and neck cancers complicate clinical management and are associated with reduced survival.
We therefore also analysed the impact of Pin1 modulation on this process by analyzing markers of epithelial-mesenchymal transition (EMT).
The expression of markers of epithelial-mesenchymal transition (vimentin, E-cadherin and SLUG) was not consistently changed by treatments also in HC-AFW1 tumours (Supplementary Figure S1).
In addition, immunostaining for vimentin and alpha smooth muscle actin, markers of epithelial-to-mesenchymal transition (EMT), was lower in diseased SM22α -/- mice compared to diseased SM22α+/+ mice.
Next we examined whether HSF1 over-expression increases markers of epithelial-to-mesenchymal transition (EMT), which has been implicated in inducing the CSC phenotype [ 10].
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