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These were predominantly markers of effective processes, such as adherence to a full physical exam and appropriate test ordering, or of effective structures such as the availability of essential supplies.
Bronchoalveolar lavage (BAL) of patients with pulmonary tuberculosis has shown increases in inflammatory cytokines and percent CD4+ cells compared to uninfected controls, and in advanced, cavitary tuberculosis markers of effective immunity are reduced.
DCM-based markers of effective connectivity between pre-specified regions of the motor network also did not indicate any compensation.
Therefore, establishing accepted markers of effective aGVHD treatment which also serve as surrogates measures of long-term transplant survival is of paramount significance for aGVHD trials.
Although no direct comparison is possible, NNTs of 5 and below are generally regarded as markers of effective treatment, but much higher values are useful for some prophylactic interventions [ 25].
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DeWitt's facility with their stories is so convincing that you wonder, briefly, if these characters are based upon historical figures -- a true marker of effective fiction.
A decrease in lactate concentrations over time is a reliable marker of effective treatment in critically ill patients with shock [22 25].
The reduction in Hes1, as a marker of effective Notch inhibition in treated cells, is also shown in Figure 2B.
Lower levels of calcium-phosphate (Ca-P) product, a marker of effective bone disease management, have also been shown to be associated with decreased mortality [ 11].
In fact, there is a relationship between MDA-EBC (a marker of lipoperoxidation of membranes) and Co-EBC, which might represent a marker of effective dose or dose at the target.
Preoxygenation is also essential for critically ill patients, but the usual preoxygenation technique appeared marginally effective in these patients regarding minimal improvement in the blood oxygen tension, as a surrogate marker of effective preoxygenation [ 12].
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