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A nested case-control study was designed within the cohort: cases with at least two depressive episodes during the 8-year follow-up were paired to non-depressed controls, antidepressant prescriptions being taken as markers of depressive episodes.
Therefore the overall aim of MR-IMPACT is to identify and evaluate objective neurobiological markers of depressive illness in adolescence and prognostic indicators of recovery following psychological treatment for depression.
The second study was a cohort study where PUFA intake was evaluated by a dietary record, and antidepressant or lithium prescriptions were used as markers of depressive episodes [41].
Despite the aim of differentiating state from trait markers of depressive illnesses in adolescence and predictors treatment response, our study is not without limitations.
Finally, excessive screen-based activity and somatic complaints might be viewed as causally unrelated markers of depressive symptoms, or a general adaptation to various stressful conditions [ 10].
However, cross-sectional studies such as these leave open the possibility that negative attentional biases are markers of depressive risk rather than causally influencing that risk.
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We hypothesized that elevated plasma concentrations of circulating CAMs associated with aging may be a marker of depressive symptoms due to cerebral vascular disease.
We hypothesized that elevated plasma concentrations of sVCAM-1 may be a marker of depressive symptoms due to cerebral vascular disease.
The first results using polysomnography to measure sleep EEG suggest that REM-density is a marker of depressive symptoms in the general population [ 359].
To identify markers of maternal depressive symptoms in medical records of children aged 1-6 years.
These studies have identified patient populations with conditions such as peripheral cancers or cardiovascular disease, as well as an incidence of depressive symptoms, and they have then assessed the patient's brains for neuronal markers of depression.
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