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A similar sequence in brain markers of decline was characterized in individuals showing memory loss manifested first by decline in functional neuroimaging (PET-CBF) followed by structural brain changes (MRI) then cognitive decline (Clark et al. 2012).
With advances in neuroimaging, segmentation of these structures can be completed with automated programmes which are widely available, reproducible, and thus, if these regions prove to be markers of decline with repetitive traumatic brain injury, they have the potential to become clinically useful and readily calculated biomarkers.
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Is sensory impairment an early marker of decline?
Fear of falling (FoF) is present in 20% to 85% of older adults and may be an early marker of decline in global cognitive functioning (GCF).
His last, Dear Heather, was a weak effort, a marker of decline.
We found that glucose abnormalities (on the OGTT and CGM) and markers of clinical decline (fall in wtSDS or lung function over the preceding year) were common and were not limited to those with the more severe genotype with homozygous F508del or to those with exocrine insufficiency.
Unfortunately, SCr is a late marker of declined kidney function and does not adequately reflect damage to kidney cells.
For this reason, differences in variability of reaction time on the SART are generally a more reliable marker of declining sustained attention than mean reaction time.
In this context, the data presented here suggest that more variability in the executive aspect of sustained attention may represent a potential marker of declining sustained attention that is associated with falling.
The markers of European decline are not hard to find.
Different genetic markers of diversity decline at different rates, creating an imbalance.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com