Guo, Q. et al. Identification of novel genetic markers of breast cancer survival.
In breast tumors, the level of BST-2 is significantly higher when compared to notable markers of breast cancer, including estrogen receptor, progesterone receptor, HER2, or Myc6.
McCormack, V. A. & dos Santos Silva, I. Breast density and parenchymal patterns as markers of breast cancer risk: a meta-analysis.
In the last 20 years, arrays of potential prognostic and/or predictive markers of breast cancer have been analysed.
Increasing evidence suggests that BPA mimics estrogens in the body and may be associated with putative markers of breast cancer risk.
For example, high expression of the cell surface marker CD44 and low expression of CD24 are commonly used as markers of breast cancer stem-like cells (BCSLCs 14,15, whereas high expression of CD133 is a standard marker for identifying CSLCs in many brain malignancies16.
The TP53 mutation status showed strong association with the 'basal-like' and 'ERBB2+' subgroups, and tumors with mutation had a characteristic gene expression pattern.TP53 mutation status and gene-expression based groups are important survival markers of breast cancer, and these molecular markers may provide prognostic information that complements clinical variables.
Basal-like breast cancers are enriched for markers of breast cancer stem cells as well as markers of epithelial-mesenchymal transition (EMT).
ST. LOUIS, MISSOURI--Human saliva contains telltale markers of breast cancer, diabetes, and an autoimmune disease, according to new results presented here today at annual meeting of the American Association for the Advancement of Science (which publishes ScienceNOW).
There are no completely specific markers of breast CSCs, but the cells can be enriched by sorting for some markers such as CD44+/CD24- or CD44+/CD24- or or Alowhi expression (ALDEFLUOR reaction) [6], [7].
As expected, this list contains numerous markers of breast cancer cells whose expression specificity was previously reported by other (notably ERBB3, XBP1, KRT18, IL6ST, CREB1, TFF1, TFF3; see Supplementary Table S3).
