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In addition, molecular markers may identify rationale strategies for combining other targeted agents with EGFR TKIs.
Individual post-hoc analysis for each of these markers may identify the most likely multi-locus combination involving those marker.
We conclude that Bz-surviving MM cells display a GRP78HIGH/p21HIGH/CDK6LOW/P-RbLOW profile, and these markers may identify quiescent MM cells capable of fueling recurrences.
It is possible that analyses based on haplotypes of markers may identify 'rarer' disease alleles that may be present on rare haplotypes missed by single SNP analyses.
Thus, some DNA markers may identify multiple loci on the physical map, only one of which may have been genetically mapped, leading to contigs being assigned to multiple genetic locations.
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Therefore, it is not surprising that many investigators have focused on identifying new molecular markers that may identify patients with high risk of relapse despite tamoxifen therapy.
Given that type 2 diabetes is a progressive, chronic disease and typically presents in adulthood, examining markers that may identify risk in younger cohorts can offer temporal insight into the pathophysiological mechanisms of diabetes.
37 A key target for translational research is the development of new clinical imaging and molecular markers which may identify patient phenotypes in such a way as to lead to improved outcomes.
A theragnostic marker(s) may identify a high-risk cohort and there may be a predefined value for an IgG cutoff.
Researchers and clinicians have increasingly recognized that biological markers may help identify patients who are at risk for suicide.
Understanding risk markers may help identify modifiable factors which may be intervened upon, and aid in the identification of individuals at greatest risk for PDO.
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