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Recent studies of SSc genetics have indicated that different genetic susceptibility markers may determine the types of autoantibodies presenting in SSc patients [ 22, 23].
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In addition, development of species-specific immunological markers may help determine the implication of different vector species in malaria epidemics and provide further understanding of the vectorial system in a given area.
Additional studies may determine whether these markers could be used to screen cell populations before their implantation, thereby optimizing the experimental procedure and facilitating clinical transition.
In sum, the numerous markers in this category provide important clues about mechanisms that may determine the physiological and synaptic properties of HVC neurons.
Additional studies may determine the sensitivity and specificity of these cytokines as leprosy reactions markers.
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Given x then, we may determine b.
However, researchers working with a limited amount of candidate markers may opt for determining the origin of such sequence variants (e.g. occurrence of alternative splicing of pre-mRNA molecules).
Since inflammatory markers may be jointly determined with fatigue and, therefore, corresponding estimates in the fatigue equation may be biased by so-called endogeneity bias (for a general treatment of endogeneity bias, see [ 21]), we decided to correct for this potential endogeneity.
Thus, these markers may be useful to determine the implication of different vector species in malaria epidemics.
Moreover the effects of immunotherapy may need a longer time than conventional therapy; other biological markers may be necessary to determine the effect of immunotherapy and finally the development of immunosuppression especially in metastatic disease that may require a different approach [ 91].
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