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Microsatellite markers localized in the primo localization area were produced by molecular genetic approaches in BAC as described by Chantry-Darmon [39].
In three genes evidence for association with BP (P<10−3) was detected with multiple markers: intronic SNPs in LEPR and Sodium-Calcium Exchanger 1 (SLC8A1) were associated with SBP and HYP; and markers localized in Alpha-2A-Adrenergic Receptor (ADRA2A) intronless gene region were associated with DBP (Table 2).
We completed the 2140 markers map with 46 markers localized in area of low markers density.
Due to their higher polymorphism, markers localized in UTR are more interesting than markers in TR.
Heart regeneration is commonly analyzed with proliferation markers localized in the nucleus, such as PCNA, Ki-67, or pHH3 or Thymidine analogs such as BrdU or H-Thymidine.
This resulted in a map of 2140 markers that we completed with 46 markers localized in areas of low markers density [ 16].
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We examined the fetal lungs for changes in the expression of CCSP, a clara cell marker localized in upper airways.
Two markers, OsPT11 GFP, localized in the periarbuscular membrane (Kobae and Hata 2010) and GFP AM42, localized in the arbuscule, enable observation of arbuscule development (Kobae and Fujiwara 2014).
One other way to address this aim is to develop markers directly localized in the coding sequences.
In some cases, adherens junction markers were localized in circular structures surrounded by apical membrane, as in multicellular cysts (supplementary material Fig. S1), but other regions of apical membrane were not associated with junctional markers.
After finding that pathological tau staining is abundantly present and that GABAergic interneurons are reduced in the hippocampus of JNPL3 (BL6) mice we next examined if the pathological tau markers were localized in GABAergic interneurons in aged JNPL3 (BL6) mice.
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