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Because D′ is computed by dividing the minimum allele frequency for a pair of markers, it generates higher LD measures at loci with low allele frequencies than r.
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Second, our method does not use co-integrated markers and thus generates marker-free edits and does not require a specific genetic background or time-consuming selection schemes.
Assigning a P-value to a physical position requires interpolation of physical positions for markers (and intermediate markers generated in interval mapping) with unknown physical positions.
They also linked it to b-galactosidase, a commonly used enzymatic marker that generates an intense blue color when it metabolizes the sugar galactose.
Linkage analysis of the 926 markers along with 253 polymorphic markers selected from 4,449 published markers generated 21 linkage groups covering 2,166.4 cM with 1,114 loci.
Recently, single-nucleotide polymorphism (SNP) markers generated using GBS markers have been used for high-resolution mapping and identified all 19 linkage groups in M. sinensis (Ma et al., 2012).
We therefore hypothesized that the thousands of unbiased genetic markers generated through next-generation sequencing would be ideally suited to determine the origin of synchronous multifocal bladder cancer.
The other markers are generated (again depending on the image and encoding parameters) by the Init_JPEG.
Technical advances to analyze biological markers have generated a plethora of promising new marker candidates for early detection of cancer.
A total number of 458 polymorphic segregating markers was generated with AFLPs.
Besides the SSRs, 208 AFLP markers were generated with 184 progeny.
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