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With the emergence of high-throughput technologies, ranging from microarrays to next-gen sequencing, genome-wide scanning to search for disease-related DNA methylation markers is now possible.

Radiographic imaging of implanted radio-opaque markers is now feasible with electronic portal imaging.

A set of fluorescent organelle markers is now available in plants, a result of computational approaches to identify targeting motifs for each organelle [ 29- 31].

Meeting clinical action measures rather than the treat-to-target approach of surrogate markers is now more and more recommended to improve appropriateness of care [ 3, 8, 14].

Large-scale genotyping, mostly based on next-generation sequencing-based SNP markers, is now routinely performed on the same group of individual plants or animals for which phenotype assays were done.

Here, we have begun to reveal EMT marker heterogeneity in CTCs from the pancreatic cancer patients, and a more comprehensive study of their biology with simultaneous assessment of multiple markers is now underway.

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Objective: Ultrasonographic biometry markers are now being used clinically to adjust Down syndrome risk.

If they weren't before, 420-mile markers are now an endangered species.

Such markers are now being used by wheat breeders to select lines with the required quality attributes, without the need for the direct measurement of those traits in early generation screening.

He said all the 40 people before him, "his markers", were now dead.

Genetic markers are now being collected in multiple nationally representative social surveys that Conley (2009) argues can be deployed to (i) assess the direct impact of specific genetic influences on socioeconomic and behavioral outcomes, (ii) explore genetic environmental interactions, and (iii) trace genealogies across time and space.

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