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Thus, the present study has for the first time demonstrated TCRγδ clonality and CDKN2A/CDKN2B CNV together as potential prognostic markers in management of T-ALL.
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However, additional studies are required to establish the place of these markers in clinical management of patients with gastric cancer.
Carcinoembryonic antigen (CEA) is one of the most important tumour markers in the management of human carcinoma, including lung cancer.
The use of serum tumour markers in the management of non-small-cell lung cancer is not justified (standard).
Although several clinical practice guidelines have been produced for the use of serum tumour markers in the management of breast cancer, the practice remains inconsistent (ASCO, 1996; ANAES, 1997; Bast et al, 2001; Mauriac et al, 2001).
We believe that the interplay between clinicians and immunogenetists must be strengthened to reach a better definition of the role of HLA markers in the management of those autoimmune diseases with well-defined HLA associations.
Thus, additional testing of serum and other types of markers from other studies will be needed to identify additional molecules that can either be added to strengthen this panel or be used independently as predictive markers in the management of patients with RA who are treated with anti-TNF-α therapies.
CEA is over expressed in most colorectal cancers and is an important tumour marker in the management of colorectal cancer.
This review will discuss the feasibility of using RASSF1A methylation as a diagnostic and prognostic marker in cancer management.
More studies using a much larger sample size are needed to further define the potential role of methylated DNA marker in cancer management.
Our study indicates that the measurement of S-100B as a tumour marker in the management of patients with cutaneous malignant melanoma has clinical significance.
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