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To evaluate volatile organic compounds (VOCs) in the breath as tumor markers in lung cancer.
Gene expression of biological markers in lung tissue.
Lung morphometry and expression of biological markers in lung and diaphragm tissues in the non-ventilated groups.
Relative expression of molecular markers in lung tissue homogenate corrected with GADPH as a control gen calculated with RT-qPCR.
The effect of ATII cells was assessed by the analysis of bronchoalveolar lavage (cells and protein), proinflammatory markers in lung tissue and histological analysis.
Relative RNA expression of inflammatory markers in lung homogenate after 12 h of mice that were mechanically ventilated with high tidal volumes compared to controls.
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Jiang, F. et al. Aldehyde dehydrogenase 1 is a tumor stem cell-associated marker in lung cancer.
Next, we detected the expression level of microtubule-associated protein 1 light chain 3 (Man1LC3), autophagosomeomarkerker, in lung tissues by Western blot, and found that LC3-II expression was increased in SiNPs-treated mice (Fig. 2d).
Hence they reported sialic acid to be of value as a biologic marker in lung cancer [ 12].
Thus, the "Fibroblast specific BMP2 induced gene list" has a potential to be a prognostic marker in lung cancer.
This study suggests that the polymorphism in MMP8 is associated with a decreased lung cancer risk, which can be used as a prognostic marker in lung cancer.
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