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In addition, genic molecular markers have provided opportunities to examine functional diversity, and with the development of more genic molecular markers in major crop species, genetic diversity studies will become more meaningful.
Defined polymorphic SSR markers have provided the means to assay strain information using PCR.
Previous analyses using AFLP markers have provided evidence of asymmetric introgression in a sympatric population of O. militaris and O. purpurea in Belgium [ 16], but the mechanism causing this pattern of introgression remains unclear.
Furthermore, their low variation is particularly problematic for investigations of recent radiations such as those in the Hawaiian Islands, and indeed these markers have provided only limited resolution there.
Results based on uniparental markers have provided contradictory evidence pointing to a considerable sexually asymmetric contribution, with a predominant (92%) male European contribution [ 5] and a high (33 43%) NW African female component [ 4, 51].
Tremendous advances in bovine genome characterization over the last two decades, including the completion of the bovine genome sequence [ 1] and the development of thousands of molecular markers, have provided the necessary resources for the efficient elucidation of the genetic mutations underlying heritable disorders.
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To date, sequencing complementary nuclear markers has provided some degree of support for the deepest CO1 divergences (between the north and south-west of Madagascar) as being separate species.
The use of molecular markers has provided greater resolution in the characterisation of the spread of infectious disease.
The development of an alfalfa Illumina Infinium SNP array containing about 10,000 SNP markers has provided a high-throughput platform [ 14].
However, analysis of proliferation markers has provided evidence of estrogen-independent proliferation of ER+, HER2+ breast cancer despite neoadjuvant letrozole [ 40].
The development of improved molecular techniques including the use of polymorphic genetic markers has provided more precise ways to identify these genetic abnormalities.
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