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Exact(6)
The diagnostic and prognostic value of 2D∶4D as a single trait marker or in combination with other trait as well as state markers has to be investigated in future studies under clinical routine conditions using internal and external validation.
This preparation led to mixed DNA of the two fungal and algal symbionts and thus symbiont-specificity of genetic markers has to be tested in lichens (Devkota et al., 2014) even if lichens contain purely fungal plectenchyma.
Therefore, the use of more than two markers has to be questioned in this context, as it does not seem to improve the NPV compared to the 2-test-combinations with high NPV.
This in turn indicates that for genome-wide association mapping in sugar beet, the number of markers has to be dramatically increased compared to the number applied in our study.
Due to the fact that r2 >0.8 is required to detect marker-phenotype association explaining less than 1% of the phenotypic variance, our observation of a low proportion of SNP loci pairs fulfilling this criterion suggests that the number of markers has to be dramatically increased for genome-wide association mapping.
Due to the fact that r2 >0.8 is required to detect marker-phenotype association explaining less than 1% of the phenotypic variance, our observation of a low proportion of SNP loci pairs showing such levels of LD suggests that the number of markers has to be dramatically increased for powerful genome-wide association mapping.
Similar(54)
However, the marker registration is associated with high logistics, since the markers have to be placed prior to data set acquisition and have to be kept in their position until the patient enters the operating room.
Finally, iv) surrogate markers had to be described.
Accordingly, the selected markers have to share regular repeat motifs across the targeted populations.
The level had been chosen to account for the fact that three biochemical markers had to be compared.
Hence, additional markers have to be identified that are associated with therapy outcome in patients with fully suppressed plasma viremia.
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