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What is more, the quantitative results demonstrated that the markers generally were more abundant in target-source fecal material than in nontarget material.
One or more additional SSTF markers will generally be needed to identify individual populations.
Although murine MSC do not have highly-specific markers, generally they are CD34neg, CD45pos, CD73neg, CD44pos and SCA-1pos [ 8, 27, 28].
It is our opinion that predictive marker studies should generally be conducted within randomised trials, require a sufficient (usually larger) effective sample size, and assays should be in a more advanced state of development.
Unlike group A markers, these markers are not generally accepted as markers of clinical relevance by themselves (risk factors), but there is ample evidence from relevant subpopulations that (alterations in) these markers are associated with (alterations in) clinical outcomes, and this is supported by a plausible mechanism of action.
Inconsistencies between subjects' sex and X chromosome genotypes may reveal some problems, and in family studies, some errors may be revealed through Mendelian inconsistencies at markers, but we will generally be blind to most errors.
In a clinical setting where a number of treatment options with similar impact on patient outcome are available, the utility of a predictive marker for individualised therapy would generally be greater than the utility of a prognostic marker.
Indeed, just two 0.6-mm cores, rather than the six used here, may be sufficient to represent staining seen on an entire histological section, even for markers generally thought to be heterogenous [ 21].
As microsatellites are generally not as amenable to inter-generic studies as some other types of markers they are generally synthesized for each genus or species.
Until now, the SSR markers generally deployed in wheat genomics were mainly obtained from genomic libraries, and only a limited number of DArT markers (up to 2,000) have been sequenced in wheat (http://www.diversityarrays.com/DArT-map-sequences).
The markers used are generally assumed to be representative in population genetics.
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