Exact(2)
In colorectal cancer, both intratumoural TS and DPD gene expression have been indicated to be positive predictive markers for the effectiveness of 5-FU or UFT combined with leucovorin (Salonga et al, 2000; Ichikawa et al, 2003).
In consideration of the suspected pathogenic proinflammatory effect of PGRN Abs disrupting the physiologic homeostasis of TNF-α/PGRN agonists and antagonists in a subgroup of patients with PsA, PGRN Abs might be of use as prognostic markers for the course of disease and/or as predictive markers for the effectiveness of TNF-α-blocking agents.
Similar(58)
First, CTC can survive chemotherapy and therefore can be a predictive marker for the effectiveness of treatment.
BUN, a waste product of protein catabolism, has been extensively studied in dialysis patients and is an important target for removal by (hemo) dialysis, as well as a marker for the effectiveness of dialysis.
Combined, our data suggest that endotrophin levels are a strong prognostic marker for the effectiveness of the combination therapy of TZDs with cisplatin, and neutralization of endotrophin activity dramatically improves the therapeutic response to combination therapy.
This protein can bind pRB and there is a report that E2F4 expression level is a useful predictive marker for the effectiveness of intravesical BCG therapy that can predict clinical outcomes, including recurrence, progression, and survival in patients with BC [ 26].
Therefore, some authors have proposed that the Disease Activity Score in 28 Joints (DAS28) is an inappropriate marker for assessing the effectiveness of TCZ therapy for patients with RA [ 5– 7].
The level of TSH receptor antibody (TRAb) has proven to be a good marker for monitoring the effectiveness of treatment and predicting cases of relapse and remission, especially with the developed functional thyroid-stimulating autoantibodies (TSAb) assay reported in 2012 199).
Faecal egg count is a commonly used marker in selective breeding programs for resistance to gastrointestinal nematodes and the heritability of such resistance markers predicts the effectiveness of breeding programs.
The circulating exosomal miRNAs and tumor cells can be used as noninvasively surrogate markers for the diagnosis, prognosis, and therapeutic effectiveness of metastatic colon cancers [ 33– 33].
> -wrap-foot> To evaluate the effectiveness of different markers for the study of genetic relationship in CPTs, genetic similarity coefficient was calculated.
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