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Predictive markers for response to sipuleucel-T are needed.
EGFR, p53, and MGMT expression were examined as potential molecular markers for response (Table 3).
We examined known molecular markers for response to common chemotherapy in these two histological subtypes.
Reproducible, reliable, and easily obtainable markers for response and resistance to antiangiogenic therapy are needed.
For IL-6R inhibition with TCZ, predictive markers for response have not yet been identified.
Molecular markers for response prediction were studied using gene expression profiling.
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ROS1 rearrangement can be used as a predictive marker for response to crizotinib, a tyrosine kinase inhibitor, in patients with advanced non-small cell lung cancer (NSCLC) (Bergethon et al., 2012; Shaw et al., 2014).
This study was designed to investigate the value of tumor M2 pyruvate kinase (tumor M2-PK) determination as an early marker for response to trastuzumab therapy in patients with metastasized breast cancer.
Endocrine therapies such as aromatase inhibitors (AI) and targeted monoclonal antibodies such as trastuzumab (T; Herceptin®, Genentech, South San Francisco, CA, USA) have dramatically improved breast cancer outcomes for patients with tumors bearing the appropriate marker for response: ER for AIs and HER2 for T.
Finally, CpG site No.85 can be considered as a potential marker for response to stress.
Therefore, this enzyme might be a prediction marker for response to chemotherapy.
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