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Biomarkers that can identify tuberculosis (TB) disease and serve as markers for efficient therapy are requested.
Our hypothesis is that the concentrations of MEHHP (or MEOHP) and/or MEHP% may represent phenotypic markers for efficient or inefficient metabolism of DEHP to its oxidative metabolites.
For this type of population structure, desirable marker coverage is given by Equation 2. Representative populations suggest that the number of markers for efficient QTL mapping in biparental populations is on the order of hundreds to thousands.
Despite these advantages, only ~180 microsatellite markers have been reported till to date for coffee [ 4- 12], signifying the need for expanding the repertoire of these genetically highly informative markers for efficient management and improvement of coffee germplasm resources.
These genes are not only the best markers for efficient breeding, but they are also important in understanding the mechanisms that contribute to the expression of partial resistance which still remained largely unknown.
The determination of genome-wide linkage disequilibrium (LD) patterns through the HapMap project has enabled the selection of markers for efficient genome-wide association (GWA) studies in human samples[ 8].
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Moreover, FOXP3 demethylation may represent an indirect marker for efficient suppressive capacity of Tregs.
The individual marker that showed the strongest discriminative ability for endothelial dysfunction is hs-CRP, but its usefulness as a discriminatory marker for efficient diagnosis of endothelial dysfunction should be examined in prospective studies.
Because the 3XP3 DsRed cassette was excised from the Rn-EGFP flies after initial screening, it was possible to reuse 3XP3 DsRed cassette as a selectable marker for efficient genetic screening.
In addition to selection stringency, it is also important to co-localize the GOI with the selection marker, for efficient selection and successful amplification of the GOI gene [ 3, 36].
The density of markers required for efficient GWA scans in a species is dependent on the average length of chromosome "blocks" possessing a high level of linkage disequilibrium (LD).
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