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The discovery of new genetic markers for common cancers will pave the way for tests that predict an individual's risk of disease and guide how they should be screened throughout their lives.
However, identifying genetic markers for common forms of migraine has been difficult [35].
Since then, Collins has led follow-on efforts, including the HapMap, which has fueled the search for genetic risk markers for common diseases.
However, if verified in larger series, they could be markers for common variants in BRID1/FANCJ influencing the risk.
The most promising positive SSR containing clones were used to design microsatellite primers for the development of new markers for common bean (see Additional file 1).
The robustness of the panel should be further tested with unique and highly inbred populations and the utility of the panel could be expanded by incorporating markers for common diseases or phenotypes.
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Therefore, we hypothesise that Ala946 is not causal itself but a marker for common haplotypes carrying functional variants that reduce IFIH1 transcription compared to other haplotypes with normal or higher expression.
Thus, in recent years, the efforts for finding clinically relevant genetic markers for many common diseases began also to include the 'Common Disease-Rare Variant (CDRV)' hypothesis.
To evaluate the performance of antimullerian hormone (AMH) and inhibin B as ovarian function markers for differentiating common causes of secondary oligoamenorrhea, namely hypogonadotrophic hypogonadism (HH), polycystic ovary syndrome (PCOS), premature ovarian failure (POF), and hyperprolactinemia (HPRL).
Here we characterise a panel of new microsatellite markers for the common marine flagellate Oxyrrhis marina.
We have used a combined mining strategy based on an integrated cancer microarray platform, Oncomine, and the biomarker module of the Ingenuity Pathways Analysis IPAA) program to identify potential blood-based markers for six common human cancer types.
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