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The other significant markers displayed a low MAF (4 to 7%).
The iPBS markers displayed a higher proportion of polymorphic loci (PPL = 92.5%) than the ISSR markers (PPL = 84.9%).
These markers displayed a high level of polymorphism overall (6.67 alleles/locus), though this was slightly lower within populations (3.10 4.88 alleles/locus).
Importantly, both of these routinely used markers displayed a lower prognostic accuracy than S100A6, highlighting that new and innovative biomarkers might be superior in this setting than currently used markers.
These markers displayed a homogeneous distribution at the cell surface in cells pre-treated with anti-CD3 antibodies.
In contrast, kidney endothelial cells defined by the latter markers displayed a lower expression of CD146.
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Neither of these markers displayed an apparent redistribution in ISG15 overexpressing cells relative to control cells.
Forty-two markers displayed an LOD > 3 (i.e.,%HR < 30.35%; Figure 1b), supporting the SDR hypothesis and ruling out the possibility of FDR in this population.
The discovered markers display a high level of specificity for the qPXO79_6 loci and could directly be deployed as foreground markers in marker assisted backcrossing (MABC) schemes.
Animals homozygous for DA alleles at both max markers display a 35% mean nerve cell survival as compared to 49% mean survival in animals homozygous for PVGav1 alleles at both markers.
Interestingly, all the expression profiles of Clusters 2, 4, and 5 which contain adipocytic markers display a downregulated expression profile during day 5 until day 10, which contrasts the expression profiles of Clusters 8, 1, and 7 which contain osteoblastic-associated marker genes and which show peak upregulation during day 5 to day 10.
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