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Intersection and conservation markers defined at the previous time step are discarded.
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It is much more likely that a combination of markers will be required and this may include clinical, for example olfactory function, biochemical and imaging markers to define at-risk individuals, early Parkinson disease diagnosis and progression.
The panel displayed 85.7% sensitivity, 100% PPV, 100% specificity, and 86.6% NPV when instability at ⩾3 markers defined MSI.
A few RFLP markers were defined at proximal positions within their corresponding linkage groups; however most BACs were localized to the distal regions of chromosomes.
Therefore, all canonical markers defining these subclades may be included.
While cell type-specific markers for differentiated cells are well documented (eg. contractile proteins for cardiomyocytes vs Nfatc1 for endocardial cells) such markers are less well defined at the early stages when we are isolating mRNA.
Although suitable molecular markers had yet to be defined at the time of the outbreak, recent reports on the use of the gp60 gene for subtyping in molecular epidemiologic studies (2, 3 ) have enabled us to reanalyze the isolates and report these results.
The subtypes defined by gene expression analysis have also been defined at the protein level using various markers.
The EMT process is defined at present by the observation that cells of injured tubules lose epithelial markers while they acquire mesenchymal marker proteins.
The significance level was defined at ≤0.05.
Significance was defined at the P<0.05 level.
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