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In this review, we discuss the role of established molecular markers currently used in the management of breast cancer.
First, CCL3L1-CCR5 genotypes are not only independent determinants of disease, but more importantly, they are also capturing different aspects of AIDS risk than the traditional components of AIDS risk reflected in the laboratory markers currently used to assess disease status.
In this study, we tested the hypothesis that in conjunction with laboratory markers currently used to assess AIDS risk, the complex patterns of genetic variations in the human genome may have utility as tools for improved risk assessment of patients infected with HIV-1.
Most tumour markers currently used in clinics are serum glycoproteins, frequently highly glycosylated mucins.
The challenge is to obtain a higher specificity than the traditional markers currently used.
For the selection of the 146 antibody set, we focused on markers currently used for breast cancer classification due to their value in treatment decisions (ER, PR, HER2).
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Moreover, there is no specific molecular marker currently used routinely to predict the clinical behaviour of head and neck cancer.
Despite decades of research to find suitable serum-based diagnostic markers for ovarian cancer, CA125 remains the only reliable marker currently used in the routine diagnostics.
Although the majority of assays use EpCAM as detection marker, different markers are currently used to detect and enrich CTC (Table 2).
Although antigen markers are currently used to identify subplate neurons (e.g., Map2, CSPG, Tbr1), the expression of these markers is not restricted to subplate neurons.
These tables clearly indicate that a subset of markers have already proven useful for investigating efficacy in RA, although surprisingly few combinations of MRI and biochemical markers are currently used.
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