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> -wrap-foot> Because the analysis focuses on the evaluation and ranking of markers and not on assays used to measure these markers, criteria for analytical validation were not included.
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These detailed expression profiles allowed the identification of eight genes best fulfilling the ideal marker criteria.
In conclusion, to the best of our knowledge this is the first report of a single molecular prognostic marker criterion for low-grade glioma survival in adults.
Even those utilising similar markers and criteria for AKI - for example, the RIFLE criteria [ 2] (two studies) or blood urea and nitrogen (four studies) - utilised and interpreted them in very different ways when distinguishing early and late initiation of RRT.
And the unfortunate truth is that it is still far too early to use biological markers as criteria for diagnosis.
First, the differences in methylation markers and criteria for CIMP may result in inconsistence.
Because of the different methylation markers and criteria for CIMP, we could not systematically analyze the association between CIMP status and CRC prognosis upon meta-analysis to obtain a stable result.
The aim of this study was to conduct a comprehensive systematic review on neonatal near miss, searching for studies in the scientific literature that analyzed neonatal morbidity markers as criteria for identifying and defining neonatal near miss.
To our knowledge, our study is the first that compared promoter methylation in a large group of multiple localizations of distant human breast cancer metastases to their matched primary breast carcinomas and we tried to apply the "reporting recommendations for tumor markers" (REMARK criteria) as adequately as possible [ 21].
This biological marker study was performed in accordance to the reporting of tumour marker studies criteria (REMARK).
Inference based on this method does not depend on the modeling assumptions and also requires no special marker selection criteria.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com