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On the other hand, Stuxnet's authors were uncommonly thorough about not leaving clues in their code; the markers could have been deliberately planted by someone who wanted to frame Israel.
Importantly, EGFR and c-Met were highly expressed in this subset, suggesting that antibodies against these cell surface markers could have utility in capturing this subset of breast cancer cells.
First, the lack of significance in the levels of various markers could have resulted from the relatively small patient groups.
It is possible that additional markers could have been identified if the number of clones selected from the LNCaP cDNA library had been enlarged.
With that approach and those sample sizes, any misclassification of lines or mis-scoring of markers could have considerably expanded the estimated distance between loci.
Linking more specific response biomarkers with existing radiographic markers could have a significant impact on our ability to diagnose and treat ARDs.
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However, a missing allele at either marker could have been due to a recombination event.
Nor do we believe that the addition of the marker could have interfered with the detection of structuring.
In our previous paper we reported, that higher concentrations of 8-IP in EBC are found in a more extensive disease (radiological stage III), that raises hopes, that this marker could have a prognostic value [ 9].
Furthermore, several factors related to the biochemical characteristics of each marker could have disturbed the concentrations of serum proteins such as the coagulation and fibrinolysis factor and leukocyte degraulation [ 27].
Moreover, in this setting, with more difficult tumours to diagnose, the addition of a good diagnostic tumour marker could have been of great importance, and yet, the addition of HE4 to CA125 does not seem to fulfill these expectations.
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