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Even our most closely linked markers are too sparsely located for association mapping in these populations.
However, RFLP markers are too labor-intensive and high cost for applied use, as well as having potential health and environmental hazards.
Increased emphasis should be given to higher resolution RH and other physical mapping data to resolve order where placement of linkage markers is uncertain, and markers are too close to provide definitive order.
Traditional methods including meiotic fluorescence in situ hybridization (FISH) and translocation lines can be used to precisely locate DNA markers to chromosomes, but most markers are too small to be used directly as probes in FISH.
Because some people believe that there are mechanisms causing LGT that could be important in prokaryotes, they sometimes proceed to some further phylogenetic analyses, which generally suggest that phylogenetic markers are too weak to tell about the extent of LGT, or even show some conflicting signal.
Refrain from using crayons and markers since markers are too dark and messy and crayons aren't dark enough.
Similar(54)
Third, this meta-analysis did not include several important risk markers because the number of studies examining these risk markers was too small.
While these endosomal markers were too dim to observe colocalization in the neurites, we were able to examine colocalization in the neuron cell bodies [55], [76].
These results indicate that the sensitivity of the traditional ESCC tumor markers is too low to diagnose esophageal cancer diagnosis.
Generally, the variability in the concentrations of neuropeptide markers is too great to draw any definitive conclusion in those who were depressed and also displayed suicidality.
That is, a linear model that consists of p markers is too complicated for the prediction of BVs of n individuals.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com