Hence, as in a model that fits only pedigree relationships (y = 1μ + Z1 a + e), the total genetic variance is explained by the A matrix and the segregation of chromosome segments that are traced by the markers is explained by σ u.
We find that significant amounts of the genetic variance in all marker systems are explained by among-population structures.
The inconsistency of some markers can be explained by the tight linkage among different marker pairs, inadequate data (missing data), and differences in segregation information among markers and populations57.
We also performed association test conditional on rs1421085 (the most significant marker) to investigate whether the significant association signals between "body fatness" measures and "body fatness" markers can be explained by a single locus.
In the NK603 study, statistically significant strong urine ionic disturbances and kidney markers could be explained by renal leakage [5], which is well correlated with the effects of glyphosate-based herbicides (like Roundup) observed on embryonic kidney cells [23].
The lack of change of the other markers might be explained in part by the relatively short study duration.
The associations between "body fatness" traits and the "body fatness" markers could be explained by a single SNP without any clear sign for allelic heterogeneity.
Aside from differentiation, lower expression of these surface markers might be explained by the influence of the tumour microenvironment.
In this respect, Figures 3E and G, showing more tdTom cells than with cardio markers, should be explained better.
