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Functionally, these markers are enriched in ontologies involved in hormone synthesis, processing and regulated secretion.
These facts strongly indicate that mPing-SCAR markers are enriched in euchromatic, gene-rich regions.
Both in silico and experimental validation efforts demonstrated that these markers are enriched for single orthologous loci that are homozygous for alternative alleles.
As noted, the results do support the possibility that the selected markers are enriched for true associations to the humoral immune response to influenza vaccine.
Not surprisingly, most of these nine histone markers are enriched around the transcription start sites of protein coding genes and a peak of RPM can be found near the TSS).
These in vivo tumorigenesis studies for both cell types indicate that Brca1 cells bearing distinct cancer stem cell markers are enriched at least 50-fold to 100-fold in tumor-initiating cells.
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Acetylation of histone H3 at Lysine 9 (H3K9Ac), one of the most well known epigenetic markers, is enriched in the promoter region of activated genes [22] [25].
For instance, in AT1 cells and MEF26 cells both active and repressive histone modification markers were enriched whereas, repressive histone modifications were significantly diminished in AR1 cells that express a high level of Hoxa9.
As expected, the representative population markers were enriched in the appropriate groups (Fig. 1d) [ 32– 32].
All markers were enriched in their respective fractions and a prominent signal for VAPB was obtained in the MAM fraction (Fig. 3A).
In the vast majority of the cases both markers were enriched at the same centriole pair, indicating a robust recognition of the old centrosomes (data not shown).
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