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Several studies showed the association between inflammatory markers and type 2 diabetes [ 26, 27].
However, clinical or observational data showing associations between oxidative stress markers and type 2 diabetes are scarce [ 5].
We investigated the association between leukocyte telomere length, the UCP2 variant (−886G>A), recently identified serological markers, and type 2 diabetes in a Chinese population.
A total of 930 patients and 867 control subjects were recruited to examine the association between leukocyte telomere length, UCP2 variant (−886G>A), recently identified serological markers, and type 2 diabetes.
Since circulating liver enzymes including aspartate aminotransferase (AST), alanine aminotransferase (ALT), and Gamma glutamyltransferase (GGT) are commonly elevated in asymptomatic patients with NAFLD [ 5, 6], the prospective association between the hepatic markers and type 2 diabetes is expected, as has been reported in many longitudinal studies [ 7- 12].
The populations used for the analysis, the number of animals in the reference (N ref) and in the validation set (N val), total number of animals (N total), number of markers (N markers) and type of response variable (Phenotype) used in the prediction models.
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We measured biological markers and typed human leukocyte antigen genes DR and DQ.Novel predisposing factors were identified including increased birth and developmental problems (odds ratio, 6.5).
Although results are promising for extracts from intravalvular liquid in oyster, it is unlikely that a single protocol could be the best across all bacterial markers and types of shellfish.
The complete description of markers and types of assay used for the purpose of this analysis is reported in Table S1.
For each eligible study, the following information was extracted: first author with year of publication, racial descent of study population, number of families and affected individuals, numbers of case control subjects, number of markers, and types of statistical analysis.
The two pairs of primers were treated as two individual markers and typed separately on the IMNpRH212,000-rad panel, where they served as internal controls to evaluate mapping accuracy and resolution.
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