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Statistical significance of trends between markers and standard prognostic variables was assessed using the Mann–Whitney U and Jonckheere Terpstra tests.
Tissue sections proximate to those demonstrating the presence of donor cells by FISH were interrogated with antibodies for various cell fate markers and standard H&E staining (Fig 3F).
Our studies indicate that a multivariable survival model including both molecular markers and standard clinical/pathological markers is significantly superior to a model based on either group of variables alone.
We performed cross-validation analyses to assess performance of multivariate Cox models consisting of these markers and standard clinico-pathological covariates, using an average time-dependent Area Under the Receiver Operating Characteristic curves and compared it to nested Cox models obtained by robust backward selection procedures.
In experimental research, the assessment of immunotoxicity in animal models should go beyond characterization of immune parameters (i.e., cell subsets, cytokine production, cell surface markers) and standard measures of function (i.e., sheep red blood cell response, lipopolysaccharide stimulation) to models that incorporate analysis of response to infectious agents.
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Item 17 of the REMARK guidelines recommends that results should include 'an analysis in which the marker and standard prognostic variables are included, regardless of their statistical significance'.
To analyze oxidative stress markers and seminal standard parameters after using resveratrol (0.1, 1.0, and 10.0 mM), an important antioxidant, in the cryopreservation of human semen.
We recognise that our findings need to be confirmed in another population of breast cancer patients, ideally, one with data on inflammatory markers and the standard breast cancer data.
Table 5 shows mean estimates of the quadrivalent-to-bivalent ratio τ, the probability of a pairing-partner switch between the two markers pDP, and the probability of a pairing-partner switch between the centromere and the centromere-proximal marker pPC and standard deviations of the estimates, expressed relative to the true values.
Bilateral gait assessment was performed using a published marker set and standard methods [ 36, 37].
However, currently within the South African public health sector there are no uniformly agreed-upon quality markers and accreditation standards for our ECs.
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