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In this study, genetic deficiency in IL-17A ameliorated SA-AKI markedly, as demonstrated by reduced mortality, improved inflammatory markers, and reduced neutrophil infiltration, which demonstrated a critical role for IL-17A in SA-AKI.
The tail vein infusion of AFP-NOS 3/RSV-Luciferase adenovirus increased cell death markers, and reduced cell proliferation of established tumors in fibrotic livers.
The hallmarks of bradyzoite differentiation are the expression of bradyzoite specific markers and reduced replication rate [8].
As a consequence, Strauss and colleagues reported a down-regulation of activation markers and reduced secretion of several cytokines including IL-2, IFNγ or TNFα.
In addition, ectopic overexpression of miR-449a in HCC cells promoted the expression of epithelial markers and reduced the levels of mesenchymal markers.
Treatment of compound mice with an iNOS inhibitor decreased DNA damage markers and reduced early β-catenin lesions and tumor load.
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Deficiency of FGF21 in the heart was demonstrated to induce of cardiac hypertrophy markers and reduce fatty acid oxidation [ 37].
Parenteral iron preparations (intramuscular and intravenous) when compared to oral iron, were reported to improve haematological markers and reduce the incidence of anaemia at term.
We first estimated local allele frequencies along all chromosomes by applying a simple sliding window approach that estimates the local allele frequency for 1000 adjacent markers and reduces the noise in uncovering the distribution of the read counts.
The logistic regression analysis revealed higher levels of oxidative stress marker and reduced level of TAS were significantly associated with breast cancer.
miR-221/222 induced EMT-like characteristics, with enhanced invasion and migration, increased levels of the mesenchymal marker vimentin and reduced levels of the epithelial marker E-cadherin.
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