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We will discuss current advances on definitions, molecular markers and function of cardiac fibroblasts in heart homeostasis and disease.
The hAF-MSCs were differentiated into endothelial cells under the induction of vascular endothelial growth factor (VEGF) and analyzed for the expression of the endothelial-specific markers and function.
Looking deep inside the immune system we can find a dynamic and complex environment of cells that are different in type, size, complexity, markers and function.
ILC2s in mouse and human have similar markers and function, although CRHT2 is specific for human since mouse ILC2s do not express this marker (Table 2).
These three groups of cells share similar molecular surface markers and function, and finally they were collectively named as group 2 innate lymphoid cells.
In both humans and mice there are several subtypes of DCs, as characterized by surface markers and function.
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Upon FACS purification based on CD31+ expression, the hiPSC-EC population was observed to display typical endothelial surface markers and functions.
Conventional DMSO-mediated differentiation of HepaRG cells was performed through culturing cells for two weeks in the absence of DMSO, following by two additional weeks in the presence of 2% (vol/vol) DMSO, in order to promote expression of differentiated hepatic markers and functions, as previously described1.
Adipocyte-related markers and functions were examined in vitro in response to adipogenic culture conditions for 21 days in comparison to early passage MSCs and late passage MSCs ex vivo expanded on TCP.
The ability of the DC matrix to preserve adipocyte-related markers and functions of MSCs following extensive ex vivo expansion represents a novel culture technique to expand functional adipogenic progenitors for tissue engineering applications.
Similar markers and functions are found in both mouse and human ILC3s with the exception that mice do not express NKp44 (Killig et al., 2014).
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