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Since the effect of homozygosity on PESCs pluripotency and differentiation potential is unknown, we assessed the similarities and differences in pluripotency markers and developmental potential by in vitro and in vivo differentiation of homozygous and heterozygous PESCs.
Since the effect of homozygosity on PESCs pluripotency and differentiation potential is unknown, we assessed the similarities and differences in pluripotency markers and developmental potential by in vitro and in vivo differentiation in two genetically distinct PESC lines.
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Gangliosides serve a variety of functions such as cell type-specific markers, differentiation and developmental markers, receptors, and as mediators of cell adhesion [9].
In summary, all these molecules represent non-invasive candidate markers for physiologic and developmental analysis of the lactating mammary gland.
Because Wallerian degeneration is well known to involve cytoskeletal disassembly and because caspases are recently implicated in aspects of this process, we asked whether antibodies directed at caspase-generated neoepitopes of beta-actin and alpha-tubulin would be useful immunohistochemical markers of pathological and developmental axon degeneration.
Also, degenerating cells, more frequently in older brains, might (re-) express immature markers and falsely suggest developmental events.
This gene set comprises 82 validation targets from Tag-seq analysis, eight glioma and developmental markers, and three endogenous control genes (18S ribosomal RNA, TUBB and NDUFB10).
Germ-line mutations of the mouse have for years comprised one class of biological markers for mammalian reproductive and developmental toxicology.
One physical characteristic that may inform health judgements is fluctuating asymmetry as it may act as a visual marker for genetic quality and developmental stability.
The selective expression of keratin genes is highly tissue-specific, and antibodies to keratins have long been used as markers of differentiation in cell and developmental biology and in pathology applications.
This is in line with the aberrant expression of developmental markers and induction of apoptosis observed in Ring1b knockout ES cells.
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