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Similarly, another set of 46,270 BAC-end sequences for CAH1 library that were used to develop novel SSR markers and development of high-density genetic map in chickpea were also used for in silico mapping onto draft chickpea genome during the present study.
Further validation of markers and development of molecular tests is indispensable for the reliable up- or down-staging of LNs.
In addition, long-term spheroid-forming assay may allow rapid screening of tumors for enrichment in cancer stem cells, identification of additional stem cell markers, and development of potentially curative therapies that target the putative cancer stem cell.
Better understanding of pathogenetic mechanisms may hasten identification of new prognostic markers and development of new diagnostic and therapeutic strategies against this deadly disease (Villanueva et al, 2007; Calvisi et al, 2012).
Molecular markers and development of statistical techniques to analyze such data have been the subject of recent intensive studies [ 10- 21], allowing the analysis of the genetic structure in several species and eliminating many of the problems linked with spurious associations.
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To adopt new methods of control, a number of important issues must be addressed such as environmental-based interventions, novel drug discovery, the next generation sero-markers and development of new strategies for parasite control, and so forth.
Understanding these complex networks is extremely important for prognostic markers discovery and development of new therapeutic strategies [7].
This review summarizes recent studies exploring the role of LDH-5 in cancer growth, its utility as a tumor marker, and developments made in identifying and designing anti-LDH-5 therapeutic agents.
PPT-tolerance genes are vital in both plant biotechnology as selectable markers and the development of transgenic herbicide-resistant crops.
There was minimal toxicity, with no significant elevations in autoimmunity markers and no development of new T2 abnormalities.
MAG participated in conceiving the study, coordinated the SSR and STS markers development and analysis, and participated in drafting the manuscript.
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