Cell lines established from OS recapitulated characteristics of the primary tumor, including the expression of mature OB markers and ability to form mineralized tumors when transplanted.
The authors in both studies showed that prolonged treatment of cells with TGFβ1 enhanced expression of markers associated with EMT and many properties of stem cells which include expression of cell surface stem cell markers and ability to form mammospheres.
In the present study, we examined not only cell markers and ability to differentiate, but also other characteristics, such as imprinted genes, DNA methylation and X chromosome inactivation.
The DC lineage is divided into several subtypes based on transcription factor requirements, surface markers and ability to prime CD4 vs CD8 T cell responses.
Here we use the term subepicardial ECs to describe the ECs of a primary subepicardial vascular plexus, which is assessed by their lack of differentiation markers, and ability to become either artery or vein.
Comparisons of the discrimination ability for DArT markers and their ability to reflect pedigree backgrounds in contrast to other marker types is made much simpler when over-lapping sets of germplasm are used in a number of studies.
These tumor cells, referred to as CSCs, tumor-initiating or tumorigenic cells, are distinguished by a combination of operationally defined common or unique cell surface associated markers and the ability to establish the disease in appropriate recipient mice [4].
Thus, the GRGs provided prognostic information with three unique characteristics, (i) independence from the AIDS risk conveyed by the viral load and CD4 cell count; (ii) equivalence in magnitude to the laboratory markers; and (iii) ability to correctly predict AIDS risk in spite of contrary information imparted in some instances by the viral load and CD4 cell count.
ASThiPS lines were indistinguishable from human embryonic stem (ES) cells based on the expression of pluripotent markers and the ability to differentiate into the three embryonic germ layers in vitro by embryoid body generation and in vivo by teratoma formation after injection into immunodeficient mice.
A stem cell population is characterized by the lack of differentiation markers and the ability to undergo multi-lineage differentiation.
