These data suggest that RYE is a marker of sleep drive (the increased desire to sleep after wakefulness), with the levels of RYE being controlled by the homeostat.
SWA has been established as a marker of sleep homeostasis, as it increases in proportion to prior wakefulness and declines with sleep [ 19, 20].
13 Increased slow-wave activity (SWA) in nonrapid eye movement (NREM) sleep, a marker of sleep intensity, was observed in the brain regions stimulated by intense activities during wakefulness both in humans and animals.
The impact of this common genetic variant for efficient treatment of hypersomnolence and behavioral markers of increased sleep need after sleep loss is controversial.
Emotional stress may affect latencies to sleep onset, to REM-sleep and other markers of sleep disruption such as arousals.
The design allows for: (1) the first test of a sleep intervention in this population; (2) the comparison of sequenced CBTi and CPT to attention control followed by CPT, and (3) assessing the roles of neuroendocrine function, inflammatory processes, and objective sleep markers in mediating treatment outcomes.
Our data provided new insights into their contribution to subtle process managing SWS quality and its efficiency rather than SWS quantities, as evidenced by the deleterious impact on two powerful markers of sleep depth, i.e., SWS consolidation/fragmentation and SWA intensity under basal condition and under high sleep pressure.
SWA and SWE putative markers of sleep homeostasis were higher after chronic PSD.
Specifically, we investigated sleep duration, eating behaviour and circadian characteristics as well as ghrelin and leptin plasma values as possible markers of sleep and intake-related processes.
The lack of significant correlations in this and other studies between the PSG parameters and neurocognitive functioning may be due to the limitations inherent in the PSG parameters currently recorded in children, especially their insensitivity to more subtle markers of sleep fragmentation such as sub-cortical arousals which are not routinely quantified.
