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Exact(7)
In this manner, each marker would have a value representing the number of individuals in the sampled population which shared the marker (the sum of the row) and each individual would have a value representing the total number of markers scored for that individual (the sum of the column).
For the harmonized set of 13 populations, this marker would have an average MAF of 3.8% across all populations, and would be dismissed under a 5% threshold.
This maintains the size of microsatellite as evolutionary constraints otherwise microsatellite marker would have been always increasing in length during course of evolution.
The ideal marker would have high specificity toward cancer cells relative to normal cells and the target(s) would be represented on a high proportion of tumor types.
As such, any given marker would have an approximately 0.2% chance of falling within a swept region, necessitating an extremely dense screen in order to identify adaptively important loci.
Ideally, a good marker would have an optimal evolutionary rate for the given phylogenetic question, equilibrated and homogeneous base frequencies [ 30, 31], and homogeneous distribution of site variability [ 11].
Similar(53)
But more narrative markers would have been helpful, not least to ground the play and give it some dramatic interest.
Second, an insufficient number of genetic markers would have equally affected our ability to estimate genetic dissimilarity between mates.
First, to determine whether the CCL3L1-CCR5 GRGs conveyed a reduced or increased AIDS risk in settings when the laboratory markers would have suggested an opposite risk, we employed the likelihood ratio (LR) statistic.
Under conventional methods, some markers would have been discarded entirely without further consideration.
Such markers would have applications to both routine clinical practice and research.
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CEO of Professional Science Editing for Scientists @ prosciediting.com