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The definition of C3 marker and C3-C4 marker were defined in Methods.
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Three kinds of marker are defined in the model: start areas, places (sets of cells) were pedestrians are generated: they contain information for pedestrian generation both related to the type of pedestrians and to the frequency of generation.
A partition for each marker was defined.
A 10%% increase in tumour marker was defined as biochemical progression.
Thus, a gene marker was defined as positive if it was detected by dot blot and not by PCR.
A plateau in the tumour marker was defined as a less than 15% decrease or increase on two occasions.
A predictive marker is defined as a biological factor, which can predict clinical outcome in treated patients.
The cutoff value for each marker was defined as the marker fold change that corresponds to the point on the ROC curve closest to the point (0, 1).
A rise or fall in the tumour marker was defined as a greater than 15% increase or decrease in the marker on two consecutive occasions 3 weeks apart.
A biomarker or biological marker is defined as an indicator of a biological state or existence in the past of a particular type of organism.
Then an ancestral marker is defined by each alignment which has at least an occurence in two extant species whose evolutionary path goes through the boreoeutherian node.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com