Based on the results from our molecular analysis of hypertrophic markers, we hypothesized that the deficiency of dystonin in dtTg4 mice would lead to signs of cardiomyopathy at morphological and histological levels.
Because adaptive differences occur in the absence of detectable divergence in neutral markers, we hypothesize that selection on these traits in swamp sparrows is sufficiently strong to override recent divergence and/or ongoing gene flow from inland populations.
Second, we restricted this study to two polymorphic markers that we hypothesized to be significantly associated with the disease.
On the basis of the differential marker expression profiles, we hypothesized that NP-R clones represent a NP stem cell progenitor-like phenotype, whereas the NP-nR clones might have been immortalized at a more advanced differentiation or maturation stage.
As mentioned above, gene expression studies have revealed that VSELs express several epiblast and germ line markers and we hypothesize that VSELs originate from early epiblast-derived migrating primordial germ cell (PGC -like cells, are dePGC -likeuring development in adult tissues as a sourcells TCSCs, are play a role in organ rejuvenation [ 76, 77].
The DXS1047 marker showed the highest LOH (47.23%) of the markers tested, and we hypothesized that the regions adjacent to DXS1047 contain one or more candidate TSGs with important roles in breast carcinogenesis but not in other kind of cancers (Table 1).
Moreover, they suggest that one subpopulation is upregulating luminal markers (Krt8), and we hypothesized that this is the BLP.
As a marker of cardiometabolic diseases, we hypothesized that dietary Neu5Ac could have far-reaching effects on cardiometabolic indices in view of the widespread incorporation of SA into multiple tissues in the body.
As suPAR has been proposed as a biologic marker of fibrinolysis and inflammation, we hypothesized levels of suPAR to be elevated in lung-lavage fluid of burn patients with inhalation trauma and to correlate with markers of inflammation and coagulopathy.
We hypothesized that markers of endothelial function increase over pregnancy but decrease with smoking.
