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Survey genotyping to test the purity of accessions can be done with various molecular marker types such as inter-simple sequence repeats (ISSRs) or AFLPs.
Among these tools, genetic maps have been constructed mainly using marker types such as simple sequence repeats (SSR), restriction fragment length polymorphisms (RFLP) and amplified fragment length polymorphisms (AFLP) in different mapping populations.
Other marker types such as SCAR (Sequence Characterized Amplified Region) and CAPS (Cleaved Amplified Polymorphic Sequence) have also been produced and used to construct genetic maps, but the limited number of markers with polymorphism between different lines in a species does not meet the need of fine mapping.
Co-dominant markers also provide more complete information in QTL mapping studies [e.g. allowing estimation of additive and dominant allelic effects; [ 38] and are more useful in some genetic analyses, such as estimating population genetic parameters (e.g. inbreeding levels), relative to dominant marker types such as DArT.
The final chapter of part III, chapter 22 discusses blood-based biomarkers for VEGF inhibitors, outlines the importance of identifying and analysing suitable biomarkers and describes various marker types, such as soluble markers, endothelial cell markers, cellular markers in peripheral blood and markers found within other cell populations.
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In addition, these maps relied heavily on a single marker type such as RFLP or SSR markers derived from limited sources.
Each of the 2 queries can be filtered according to the marker type, such as SNP and cleaved amplified polymorphic sequence (CAPS), and the name of the linkage map.
This strategy is powerful for the linkage analysis of those testcross markers that are heterozygous in one parent and null in the other, although it fails to consider many other marker cross types, such as intercross markers and dominant markers, that occur for an outbred cross.
The SSEA3-positive cells appeared indistinguishable, morphologically, from the SSEA3-negative fibroblasts; furthermore, expression of the SSEA3 antigen is not considered a marker of other cell types such as mesenchymal or epidermal adult stem cells [18], [19].
RASSF1A methylation could also be a useful diagnostic marker for other tumour types, such as breast, bladder and kidney cancer.
Thus, many molecular markers that distinguish neuronal types, such as transcription factors, or various low abundance or transiently expressed proteins cannot be used directly to reveal the morphologies of the cells in which they are [or were] expressed.
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