Exact(14)
Could our action have led to excluding regions of the genome with an unexpectedly high marker transmission ratio distortion (MTRD)?
Distortion of marker transmission ratio is frequently ascribed to selection against alleles that cause hybrid incompatibility.
This conclusion can be reconciled with evidence of marker transmission ratio distortion patterns in AF16-HK104 hybrids.
Niehuis et al. (2008) investigated the increased mortality in hybrids of N. vitripennis and N. giraulti by analysing marker transmission ratio distortion in F2 hybrid males.
Our study provides a valuable platform for conducting genome-wide association of hybrid incompatible QTLs and/or candidate genes with marker transmission ratio distortion in the hybrid.
Regardless, because of expected difficulties with sterility and/or marker transmission distortion, parents from different species should generally not be used for RPGC.
Similar(46)
On this marker set, we performed single-marker transmission disequilibrium tests (TDTs) [37] using PLINK v1.07.
These two analytic methods are both designed to detect multi-marker transmission distortion, but they accomplish this in different ways.
The multi-SNP genotype data were analyzed using two complementary statistical methods, TRIMM [15] and HAPLIN [17], to detect multi-marker transmission distortion and to look for consistency in genetic associations across the two national samples.
However, although many isolates found in the community harbor these markers, transmission of "CA-MRSA" strains between health-care settings and community may occur [ 30].
We used standard IHC detection of PrPSc in tissues as a surrogate marker for transmission of infectivity to preclinical recipient sheep.
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