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Although additional genetic events are very likely to be needed for HGSIL to ICC progression, the E2 gene disruption is a putative early marker to consider in the prognostic analysis of HPV 16 chronically infected women.
Another barcode marker to consider is ITS, which performed well in a study by Litiker and colleagues [46].
A reduction in enzyme (<10%) is a marker to consider elective treatment with rituximab, which results in normalization of ADAMTS13 activity and prevents an acute episode (Westwood et al, 2013).
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Future work may reveal whether EEEs lasting <0.8 s are useful pathological markers to consider during prophylactic studies and/or to predict later onset of PTE.
(new marker) The interviews resulted in suggestions for improvement: one of the markers, when considering the tight grading of the marking schedule, suggested that it could be widened by marking a case study out of 100 rather than 20 points, and indeed later produced her suggested schedule for the other markers to consider.
In case echocardiography is not available, our study suggests the possibility to use plasma BNP as a surrogate marker, and to consider BNP plasma level >300 pg/ ml on admission as being strongly associated with cardiac dysfunction.
In this case, marker-estimated kinships were used in a weighted log-linear mixed model that forces solutions allowing a maximum of one breed with a null contribution to the core set, in addition to weighing marker information to consider the amount of data per locus.
It has also been shown that low intensity high volume aerobic efforts produce improvements in aerobic performance markers, factor to consider since currently research in this area has shown the effectiveness of high intensity and low volume training.
In spite of the previously mentioned considerations, the stability of risk estimates in subgroup analyses, the association between MD and all breast cancer subtypes, and the persistence of its effect for at least 7 to 8 years (according to our and others' findings [ 12]), would support the use of MD as a risk marker to be considered when seeking to adapt screening recommendations.
A recent study found that a serum-circulating form of C5aR (cC5aR) may represent a new sepsis disease marker to be considered in tailoring individualized immune-modulating therapy [ 60]. cC5aR was detected in septic patients' serum at the time when the patients required continuous infusion of vasopressors or inotropic agents to maintain blood pressure, despite adequate fluid resuscitation.
Clinical prognostic studies using CD44 and CD24 as markers may have to consider both cell types.
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