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Considering the effect of the COMT genotype on the response to antipsychotic drugs, if an association is found between NIRS signals and functional polymorphisms in the COMT gene, NIRS signals could be potentially used as a biological marker to aid in the evaluation and prediction of response to medication.
Selective bladder preservation protocols use a predictive marker to aid decision-making regarding definitive treatment.
The objective of this study was to show that SHOX2 DNA methylation is a useful tumor marker to aid the diagnostic workup for suspected lung cancer.
However, we hope that CTP becomes a useful marker to aid the diagnosis of liver tumors and leads to more accurate diagnosis.
In a light of recent findings, the above mentioned RASSF1A is being considered as the potential universal marker to aid detection of fetal DNA.
EPC quantification may provide a useful marker to aid risk stratification within the context of SLE, in which the Framingham risk prediction model would appear to underestimate the risk of clinical CHD.
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Such information will lead to better understanding of tumor specific molecular markers to aid in their clinical development.
Therefore, in addition to the development and implementation of diagnostic clinical assessments, there is a need for available objective markers to aid the physician in the differential diagnosis of IPD.
Panels of immunohistochemical stains are proposed for different settings, including renal cell carcinoma (RCC) marker, CD10, and vimentin to suggest renal origin of a metastatic tumor, and markers to aid in subclassification of RCC, including parvalbumin and c-kit for chromophobe RCC, and cytokeratin 7 and alpha-methyl-acyl-CoA racemase for papillary RCC.
New markers to aid in the diagnosis and prognosis as well as to identify the optimal treatment and monitor tumor progression are therefore needed [5].
Clinical trials are ongoing to better evaluate the potential utility of these characteristics as potential diagnostic markers to aid in the identification of individuals likely to respond to the APS therapy currently under investigation.
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