In the case of severe occlusions where there are only two camera views containing projections of a given marker, the distance may become inaccurate.
This algorithm incorporates multiple sources of information, including total signal intensity and allelic intensity ratio at each SNP marker, the distance between neighboring SNPs, the allele frequency of SNPs, as well as family information when available.
As one of the leading methods, PennCNV incorporates multiple sources of information, including total signal intensity and allelic intensity ratio at each SNP marker, the distance between neighboring SNPs, and the allele frequency of SNPs.
The CNV calls and ROH calls were generated using PennCNV (version 2009Aug27) [ 6], which utilizes an integrated hidden Markov model that incorporates multiple sources of information, including total signal intensity and allelic intensity ratio at each SNP marker, the distance between neighboring SNPs, and the allele frequency of SNPs.
This algorithm incorporates multiple sources of information, including total signal intensity (LRR) and allelic intensity ratio (BAF) at each SNP marker, the distance between neighboring SNPs, the population frequency of B allele (PFB) of SNPs, and the pedigree information where available [ 27].
If the array is inserted into a telomeric region of the genome in a strain containing a NE marker, the distance between the chromosomal focus of GFP-LacI and the NE, as well as the nuclear diameter, can be measured, and each spot is assigned into one of three concentric zones of equal volume that approximates the position of the telomere within the nucleus (Hediger et al. 2002).
In addition, 2 recombinants displayed recombination between BnaA.GL and the other SSR and IP markers, the distance between these markers and the BnaA.GL gene was 0.67 cM.
Despite the heterogeneity of marker dispersion, the distance to the nearest mapped marker is less than 5 cM in most locations of the Clementine genome.
The order of the markers and the distance among markers is in close agreement with the USDA-MARC.2 genetic linkage map [ 36] except for marker pair SWR1910-SWR783, whish is reversed and separated by 14 cM instead of 1 cM.
Consequently, in regions with higher marker density, the SNP method would detect smaller COs and in regions with lower marker density the distance method would annotate smaller COs.
We are likely to put it somewhere on the spectrum between uncomfortably coarse and painfully bleak – one powerful marker of the distance between the Roman world and our own.
