In this article, we present a web-based program for generating cleaved amplified polymorphic sequence (CAPS) markers, PCR-based markers that use polymorphism in restriction endonuclease digestion patterns (snip-SNPs).
For the combined markers that used either a DNA flow cytometric abnormality or active inflammation, only 23 patients had uncertain classification due to missing DNA flow cytometric data.
We describe a new strategy for marker development that uses the available whole genome sequence for rhesus macaques.
It is a promising imaging marker that is used for targeting site-specific breast cancer [ 86].
The locations of BACs on the sequence maps are in most cases derived from the position of the (microsatellite) marker that was used to isolate that particular BAC.
Co-localizing QTLs were detected for SFW and BW, both centered on the VMC7F2 marker that was used as a cofactor for MQM analysis.
Furthermore, i-FABP levels strongly correlated with day 1 plasma levels of PCT, an inflammation marker that is used to distinguish septic from non-septic patients [ 38].
Thus, given appropriate sequence capture efficiency and sequencing depth, 92% (3787/4123) of the genes contained at least one segregating marker that was used for mapping in the population.
Ideally, the effects of treatment are monitored using the same pharmacodynamic marker that is later used in clinical practice.
Amphiregulin seems to be an important biological marker that could be used to monitor hyperinflation during mechanical ventilation in emphysema.
