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C-reactive protein (CRP) is a systemic inflammation marker that predicts future cardiovascular risk.
Thus, the patent is for a genetic marker that predicts cancer.
Our finding extends a number of recent reports from animal models on the use of ESAT-6 induced IFN-γ as an immunological marker that predicts disease progression.
It is also an adverse prognostic marker that predicts relapse of patients following radical prostatectomy [ 82].
This indicates that a marker that predicts a French sample well will also predict a German sample well.
Thus, the identification of a marker that predicts lymph node metastasis, and hence prognosis, is highly desirable.
These studies have also confirmed that EGFR mutations are a reliable marker that predicts sensitivity to EGFR TKIs (Mok et al, 2009).
Although staining for the oestrogen and HER-2 receptors are powerful individual predictors of response (and benefit from) tamoxifen and herceptin, respectively, clinicians lack a marker that predicts those who will benefit from chemotherapy.
The findings of previous attempts to identify any one mRNA or protein identified in model systems as a single marker that predicts disease-free survival have not been compelling.
Previously, we demonstrated the clinical value of c-myc as a marker that predicts response to treatment with 5-fluorouracil (5FU), the standard chemotherapeutic agent used in the treatment of colorectal cancer (O'Dwyer and Stevenson, 1998).
At N.Y.U., Dr. Ostrer and his colleagues believe that they have identified a series of genetic markers that predict the risk of a prostate cancer spreading.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com