The sensitive quantification of Human Epidermal growth factor Receptor 2 (HER2), as a key prognostic tumor marker, plays a critical role in screening, early diagnosis and management of breast cancer.
GATA-4 is a member of the GATA family of zinc finger transcription factors and is an early cardiomyocyte marker, playing an important role in transducing nuclear events that modulate cell lineage differentiation during development [25] [26] and hypertrophy of adult cardiomyocytes [27].
Highly sensitive determination of tumor markers plays an important role in early diagnosis of cancer.
CD44, one of the well-known tumor markers, plays an essential role in tumor cell differentiation, invasion, and metastasis.
In this in vitro study, we investigated whether the ROS peroxynitrite, measured by nitrotyrosine as an indirect marker, played a role in the toxic effects of hyperoxia.
Identification of these molecular markers plays a significant role in monitoring and assessment of drug resistance as well as in designing an effective antimalarial drug policy in India.
The quality of ARToolKit markers plays a vital role in the performance of Augmented Reality applications, but currently there is no algorithm or quantitative measure to guide users for designing high quality markers and their reliable tracking.
Identifying and scoring cancer markers plays a key role in oncology, helping to characterize the tumor and predict the clinical course of the disease.
In addition, the up-regulation of biglycan and decorin, as well as TGF-β itself, indicate that regulation of TGF-β, and other profibrotic markers plays a role in IgAN pathology.
Conversely, degradation of nuclear β-catenin in sea urchin leads to expansion of apical ectodermal genes including nk2.1, foxq2, six3, rx and fgfR[ 27], indicating that Wnt-mediated antagonism of apical plate markers plays a role in the development of apical territories in deuterostome and cnidarian larvae.
