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Third, we chose to use unconventional measures of marker performance.
Receiver operating characteristics (ROC) curves were plotted to quantify the marker performance.
These quantitative algorithms did not improve overall marker performance (see Supplementary Table S2).
Receiver operating characteristic (ROC) curve methods were used to quantify marker performance both graphically and statistically [34].
Next we turned to the analysis of marker performance with respect to the different types of polyps analysed in our study.
Primers, basic marker performance measures and single point transmission disequilibrium test (TDT) results as determined using Unphased v3.08 [29] are available for each marker in Supplementary Table S2.
Similar(32)
Again, these results showed that marker performances were extremely close to each other.
As expected from the single-marker performance, the identification of mild current-activity synovitis (RA patients) was even better when combining markers into panels (Table 3 and Figure 2, right panel).
Future studies should include more patients to assure a better assessment of the novel markers' performance.
A systematic review of serum and urine biomarkers in knee and hip OA provides an overview of publications on biochemical markers performance [ 32].
However, patients with HPV infection should also be enrolled in future studies to assess the influence of HPV on the markers' performance.
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