Sentence examples for marker of unfavourable from inspiring English sources

Data from this study suggest that PRMT1 gene variant v1 expression may be used as a marker of unfavourable prognosis for colon cancer patients.

However, although plausible mechanisms have been proposed to suggest that impaired kidney function may itself be a causal factor in coronary heart disease, 30 the possibility remains that chronic kidney disease is chiefly a marker of unfavourable cardiovascular risk profiles.

Additionally, ADAM9 expression is significantly associated with markers of unfavourable prognosis.

The specific MdPME2 gene highlighted in this study could be a good early marker of texture unfavourable trait in apple.

Thus, methylation status of the APC1A tumor suppressor gene promoter has been suggested as a novel marker of an unfavourable outcome in cervical cancer, i.e. prognosis is worse with an increase in promoter methylation [ 9].

In other types of cancer, HIF-1α was a marker for unfavourable prognosis, such as in early-stage invasive cervical cancer.

PAI-1 plasma levels at the time of diagnosis are markers of an unfavourable prognosis in patients with severe sepsis.

Interestingly, in the present and to date most comprehensive study of KRAS alterations in primary and metastatic lesions from endometrial carcinoma patients, we find that high KRAS mRNA expression and KRAS amplification, in contrast to KRAS mutation, are associated with a large range of surrogate markers for unfavourable outcome and poor disease-specific survival.

A higher group number, with an increasing number of markers showing clinically unfavourable marker expression, was associated with worse survival and higher distant recurrence rates.

This study defines EZH2 as a powerful independent unfavourable prognostic marker of CSS in patients with metastatic and non-metastatic RCC.

Analyses of the combination of all three markers showed worse clinical outcome, specifically in colon cancer patients, with an increasing number of markers showing unfavourable expression.